CHUBU UNIVERSITY
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YAMAMOTO Hisashi

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Title Senior Research Professor
Belong to Peptide Research Center
Graduated Harvard University, 1971 (Prof. E. J. Corey, Thesis Director)
Degree Ph. D.
Field of Study Organic chemistry, synthetic chemistry, biological related chemistry
Research, Studies Reaction organic chemistry, synthetic organic chemistry, asymmetric synthesis, complex organometallic catalyst, biological function related

Academic Papers, Critique

[26] Chiral Phosphoric Acid-Catalyzed Kinetic Resolution via Amide Bond Formation, Shimoda, Y.; Yamamoto, H. J. Am. Chem. Soc. 139, 6855-6858 (2017)

[25] Catalytic Asymmetric Bromocyclization of Polyenes, Samanta, R. C.; Yamamoto, H. J. Am. Chem. Soc. 139, 1460-1463 (2017)

[24] Hydroxy-Directed Amidation of Carboxylic Acid Esters Using a Tantalum Alkoxide Catalyst, Tsuji, H.; Yamamoto, H. J. Am. Chem. Soc. 138, 14218-14221 (2016)

[23] Catalytic Asymmetric Synthesis of N-Chiral Amine Oxides, Bhadra, S.; Yamamoto, H. Angew. Chem. Int. Ed. 55, 13043-13046 (2016)

[22] A Powerful Chiral Phosphoric Acid Catalyst for Enantioselective Mukaiyama–Mannich Reactions, Zhou, F.; Yamamoto, H. Angew. Chem. Int. Ed. 55, 8970-8974 (2016)

[21] Design of a New Bimetallic Catalyst for Asymmtric Epoxidation and Sulfoxidation, Bhadra, S., Akakura, M.; Yamamoto, H., J. Am. Chem. Soc., 137, 15612-15615. (2015)

[20] Catalytic Enantioselective Nitroso Diels-Alder Reaction, Maji, B.; Yamamoto, H., J. Am. Chem. Soc., 137, 15957-15963 (2015).

[19] Gadolinium-​Catalyzed Regio- and Enantioselective Aminolysis of Aromatic trans-​2,​3-​Epoxy Sulfonamides, Wang, C.; Yamamoto, H., Angew. Chem. Int. Ed., 54, 8760-8763 (2015).

[18] Chiral Bronsted Acid as a True Catalyst: Asymmetric Mukaiyama Aldol and Hosomi-​Sakurai Allylation Reactions, Sai, M. Yamamloto, H., J. Am. Chem. Soc., 137,7091-7094 (2015).

[17] Nickel-​Catalyzed Regio- and Enantioselective Aminolysis of 3,​4-​Epoxy Alcohols, Wang, C.; Yamamoto, H.,  J. Am. Chem. Soc., 137, 4308-4311 (2015).

[16] Tungsten catalyzed oxidation and ring opening to generate >99.9%ee product, J. Am. Chem. Soc., 136, 1222-1225 (2014).

[15] Ten Years Research in Chicago, Tetrahedron, 69, 4503-4515 (2013).

[14] Rapid and Stereochemically Flexible Synthesis of Polypropionates: Super-Silyl-Governed Aldol Cascades. Angew. Chem. 124, 1978–1982 (2012).

[13] Lewis Acid Catalyzed Inverse-Electron-Demand Diels-Alder Reaction of Tropones. J. Am. Chem. Soc., 131, 16628-16629 (2009).

[12] Dual-Activation Asymmetric Strecker Reaction of Aldimines and Ketimines Catalyzed by a Tethered Bis(8-quinolinolato) Aluminum Complex. J. Am. Chem. Soc., 131, 15118-15119 (2009).

[11] Cationic-Oxazaborolidine-Catalyzed Enantioselective Diels-Alder Reaction of ,β-Unsaturated Acetylenic Ketones. Angew. Chem. Int. Ed., 48, 8060-8062 (2009).

[10] Catalytic Enantioselective Pudovik Reaction of Aldehydes and Aldimines with Tethers Bis(8-quinolinato) (TBOx) Aluminum Complex. J. Am. Chem. Soc., 130, 10521-10523 (2008).

[9] Regioselective and Asymetric Diels-Alder Reaction of 1- and 2-Substituted Cyclopentadienes Catalyzed by a Brønsted Acid Activated Chiral Oxazaborolidine, J. Am. Chem. Soc., 129, 9536-9537 (2007).

[8] Asymmetric Conjugate Addition of Silyl Enol Ethers Catalyzed by Tethered Bis(8-Quinolinolato) Aluminum Complexes, J. Am. Chem. Soc. 129, 742-743, (2007).

[7] Design of Chiral N-Triflyl Phosphoramide as a Strong Chiral Brønsted Acid and its application to Asymmetric Diels-Alder Reaction, J. Am. Chem. Soc. 128, 9626 (2006).

[6] Brønsted Acid Catalysis of Achiral Enamine for Regio- and Enantioselective Nitroso Aldol Synthesis. J. Am. Chem. Soc., 127, 1080 (2005).

[5] Oxazaborolidine-Derived Lewis Acid Assisted Lewis Acid as a Moisture-Tolerant Catalyst for Enantioselective Diels–Alder Reactions. Angew. Chem. Int. Ed. Enl., 44, 1484-1487 (2005).

[4] Designer Catalysis: Combined Acid Catalysis for Asymmetric Synthesis. Angew. Chem. Int. Ed. 44, 1924-1942 (2005).

[3] Acyloxyborane: An activating device for carboxylic acids. J. Am. Chem. Soc., 110, 6254 (1988).

[2] Asymmetric hetero-Diels-Alder reaction catalyzed by chiral organoaluminum reagent. J. Am. Chem. Soc., 110, 310 (1988).

[1] Asymmetric cyclization of unsaturated aldehydes catalyzed by a chiral Lewis acid. Tetrahedron Lett, , 26, 5535, (1985).

Lectures, Symposium, Presentation

NITech International Symposium on Frontier Materials, Nagoya Insitute of Technology, 2016

Chiral China 2016, China, 2016

International Conference on Organic Synthesis at GDUT, Guangdong Uinversity, China, 2016

Pachifichem 2015, Honolulu, USA, 2015

IKOCK Symposium, Alkara, Spain, 2015

ELP Lectureship, Kyoto University, 2015

Negishi-Brown Lecturer, USA, 2015

Naito Symposium, Sapporo, Japan, 2015

Riken Symposium, Saitama, Japan, 2015

Kanagawa symposium, Kanagawa, Japan, 2015

WPI Lecture, Tohoku University, Japan, 2015

Tetrahedron Symposium, Tokyo, Japan, 2015

International Conference of Catalysis, Chicago, USA, 2014

Gordon Conference, USA, 2014

Academia Sinica, Taipei, 2014

International Conference, Prague, 2013

25th Banyu Symposium, Sappro, Japan, 2013

International Conference of Catalysis, Cologne, 2013

Roche Lecture, Columbia University, 2012

BMS Lecture, Boston College, 2012

4th EurCheMS, Prague, Czech, 2012

Natural Product Symposium, Kyushu, Japan, 2012

Vertex Lecture, UCIrvine, 2012

Abbott Lecture, Yale University, New Haven, 2012

First Germany-Japan Organocatalytic Symposium, Kyoto, Japan, 2011

Ei-Ichi Negishi Nobel Prize Symposium, Purdue, IN, 2011

European Science Foundation, COST conference, Maratea, Italy, 2011

42nd National Organic Symposium, Princeton, 2011

First Mexican Meeting on Pure and Applied Chemistry, Mexico City, 2011

Gassman Lectureship, University of Minnesota, Minneapolis, 2011

19th Lilly symposium, Madrid, Spain, 2011

Frontier in Chemical Research Lecturere, Texas A&M, 2011

ISOm, Organocatalyst Symposium, Muelheim, Germany, 2010

93rd Canadian Chemistry Conference, Toronto, Canada, 2010

N. C. Yang Lecturer, Taipei, 2010

Burgenstock Conference, Guest of Honor, Brunnen, Switzerland, 2010

The AkzoNobel, Novartis and Shasun Lecture, Bristol, UK, 2010

The Chemical Record Lecturer, Osaka, Japan, 2010

KISPOC, Kyushu, Japan, 2009

Eminent Scholar Lecturer, The University of Arizona, Tucson, 2009

The H. Smith Broadbent Lecture, BYU, Salt Lake, 2009

13th Asian Chemical Congress, Shanghais, China, 2009

ACS meeting, Milwaukee, WI, 2009

Nanyang Tec. University Opening Symposium, Singapore, 2009

Tetrahedron Symposium, Paris, 2009

The Roche Lecturer, Scripps Institute, USA, 2009

The Gilman Lecturer, Iowa State University, 2009

The Lambert Lecture, Boston University, 2009

The Third Novel Chiral Chemistry, Japan 2009, Tokyo, 2009

Chicago Organic Chemistry Symposium, Northwestern University, 2009

LOST II, Alain Krief Symposium, Namur, Belgium, 2009

Lecturer of Institute of Academia Sinica, Taipei, 2008

International Conference on Asymmetric Catalysis, Kanazawa, Japan, 2008

Tarrant visiting professor of organic chemistry, University of Florida, 2008

Suzuki Kunio Symposium, Tokyo, Japan, 2008

Banyu Foundation Symposium, Sapporo, Japan, 2008

FITS Symposium, Geneva, Switzerland, 2008

Eli Lilly Lecturer, University of Toronto, 2008

Bristol-Myers Squibb Lecturer, Berkeley, 2008

Roche Distinguished Lecturer, Colorado, 2008

Schulich Symposium on Asymmetric Catalysis, Haifa, Israel, 2008

The Japan Academy Prize Symposium, Riken, Japan, 2007

Organic Synthesis Mini Symposium, Chiba, 2007

The 5th Kitasato Chemistry Symposium, Tokyo, 2007

Invited Lecture Series, Academy of Science of the Czech Republic, 2007

The 29th annual Princeton ACS Fall Organic Symposium, Princeton, 2007

International Conference on Asymmetric Organocatalysis, Otsu, Japan, 2007

Organic Chemistry, present and future, Louvain-la-Neuve, Belgium, 2007

American Chemical Society, National Meeting, Chicago, 2007

Pierre Fabre Lecturer, French Chemical Society, Paris, France, 2006

10th International Kyoto conference on New Aspects of Organic Chemistry, Japan, 2006

6th Tateshina conference on Organic Chemistry, Tateshina, Japan, 2006

Karl-Ziegler-Professorship, Max Planck Institute, Germany, 2006

Novartis Lecturer, Boston College, Boston, 2006

Merck-Frosst Lecture, Univdersite de Montreal, Canada, 2006

Inaugural Negishi-Brown Lecture, Purdue, 2006

5th International Symposium on Chemistry and Biological Chemistry of Vanadium, San Francisco, 2006

American Chemical Society, National Meeting, San Francisco, 2006

FrontChem2006, Zushi, Japan, 2006

Organocatalysis in Organic Synthesis, Glasgow, UK, 2006

Balticum Orgnicum Syntheticum, Tallinn, Estonia, 2006

Banyu Symposium, Fukuoka, Japan, 2006

Challenges in Contemporary Chemistry Symposium, University of Michigan, 2006

Eli Lilly Lecturer, Yale University, USA, 2006

Appleton Lecturer, Brown University, USA, 2006

7th Annual Florida Heterocyclic Conference, Gainesville, USA, 2006

Reilly Lecturer, University of Notre Dame, 2006

COE meeting, Nagoya University, Nagoya Japan, 2006

PAC Meeting, Polymer Chemistry, Honolulu, USA, 2005

PAC Meeting, Inorganic and Polymer sections, Honolulu, USA, 2005

The 4th COE-Chem6 International Symposium, Tokyo, Japan, 2005

International SFB-Symposium, Aachen, Germany, 2005

Eli Lilly Lecturer, University of Pittsburg, 2005

The 22nd Summer Seminar on Synthetic Organic Chemistry, Japan, 2005

OMCOS-13, Genève, Switzerland, 2005

Novartis Lecturer, University of Illinois at Urbana-Champaign, 2005

Distinguished Merck Frosst Lectureship, Canada, 2005

125th Annual Meeting of Pharmaceutical Society in Japan, 2005

Pfizer Lecturer, Harvard University, 2005

Merck Lecturer, University of Puerto Rico, 2004

Pettit Centennial Lecturer, University of Texas, 2004

The Fourth International Symposium on Chemistry and Biological Chemistry of Vanadium, Szged, Hungary, 2004

CMDS Symposium, Seoul, Korea, 2004

10th Meeting of the French-American Chemical Society, Charleston, SC, 2004

2004 CU-Roche Colorado Symposium on Synthetic Organic Chemistry, Boulder, Colorado, 2004

The 17th Annual Organic Chemistry Day, Missouri, USA, 2004

Boehringer Ingelheim Lecturer, Alberta, Canada, 2003

Komppa Centenary Symposium, Espoo, Finland, 2003

18th International Symposium on Synthesis in Organic Chemistry, Cambridge, U. K., 2003

15th International Symposium on Chirality, Shizuoka, Japan, 2003

Otto-Bayer Lecturer 2003, Cologne, Germany, 2003

Oppolzer Lectures 2002, Genève, Switzerland, 2002

Gordon Conference, Reaction and Processes, RI, USA, 2002

BOSS IX Meeting, Namur, Belgium, 2002

Cram Stereochemistry Symposium, UCLA, USA, 2002

The Nagoya COE-RCMS Conference, Japan, 2002

ICCOC-GTL-10, Bordeaux, France, 2001

Annual Meeting of Chemical Society of Japan, Chiba, Japan, 2001

84th CSC Conference, Montreal, Canada, 2001

UCSD-Dupont symposium, La Jolla, USA, 2001

PAC meeting, Honolulu, USA, 2001

Kharasch Lecturer, University of Chicago, USA, 2000

Columbia IAP Lecturer, USA, 2000

Taiwan National Lectureship, Taiwan, 2000

218th National meeting of American Chemical Society, New Orleans, USA, 1999

37th IUPAC Congress, Berlin, Germany, 1999

Novartis Lectureship, Switzerland, 1999

9th International Symposium on Novel Aromatic Compounds, Hong Kong, 1998

12th IUPAC Conference on Organic Synthesis, Venice, Italy, 1998

1998 Hofmann Distinguished Lecture, Imperial College, London, UK, 1998

Max Tishler Prize Lecture, Harvard, USA, 1998

5th Max Tishler Memorial Symposium, Tokyo, 1997

Bio-Mega Lecturer, Montreal, Canada, 1997

William G. Dauben Lecturer, University of California, Berkeley, USA, 1997

9th International Symposium on Chiral Discrimination, Nagoya, Japan, 1997

36th IUPAC Congress, Geneva, Switzerland, 1997

H.C. Brown Lecturer, Purdue University, USA, 1997

Gilbert Stork Lecturer, Columbia University, New York, USA, 1997

ISCHIA Advanced School of Organic Chemistry, Ischia, Italy, 1996

Fargo Conference on Main Group Chemistry, North Dakota, USA, 1996

50th Anniversary Conference of Korean Chemical Society, Seoul, Korea, 1996

Annual Conference of Polymer Science, Nagoya, Japan, 1996

Organic Synthesis Lecturer, University of California, Irvine, 1996

SFC-Rhone Poulene Lecturer, France, 1995

Enantioselective C-C bond formation in synthesis, SCI, London, UK, 1995

Merck-Frosst Lecturer, Alberta University, Canada, 1995

Annual Meeting of Chemical Society of Japan, Tokyo, 1995

Pre-IUPAC International Symposium on Metal-Mediated Organic Synthesis, India, 1994

The 4th International Conference on Chemical Synthesis of Antibiotics and related Microbial Products, Nashville, USA, 1994

Merck-schuchardt Lectureship, Germany, 1994

Annual Meeting of New Swiss Chemical Society, Switzerland, 1994

Prelog Medal Lecture, Zurich, Switzerland, 1993

Fourth International Symposium on Chiral Discrimination, Quebec, Canada, 1993

Gordon Conference (Natural Product), New Hampton School, USA, 1993

Bader Symposium, Harvard University, Cambridge, USA, 1993

Annual Meeting of Chemical Society of Japan, Tokyo, 1993

Tsing-Hua Symposium on Organic and Inorganic Chemistry, Hsinchu, Taiwan, 1992

International Symposium on Inorganic and Organic Chemistry, Taipei, Taiwan, 1992

7th Johnson Symposium, Stanford, CA., 1992

First International Symposium on Organic Synthesis, Tokyo, 1992

6th Japan-Korea Organic Chemistry Symposium, Nagoya, 1992

7th International Symposium on Molecular Recognition and Inclusion, Kyoto, 1992

Gordon Conference (Organic Reaction Mechanism), New Hampton School, 1992

Nozaki Conference, Yokohama, 1992

Annual Chemical Congress of the Royal Society of Chemistry, Manchester, 1992

The 1991 Josef Fried Symposium of Bioorganic Chemistry, Chicago, 1991

Otuka Symposium on Asymmetric Reactions and Molecular Recognition, Tokushima, 1991

Japan-US Seminar, Selectivity in Synthetic and Bioorganic Chemistry, Tokyo, 1991

First Anglo-Norman Organic Chemistry Colloquium, Rouen, France, 1991

Syntex Distinguished Lecturer at University of Colorado, Boulder, USA, 1991

Symposium of Ohio State University, Recent Advances in Asymmetric Synthesis, USA, 1991

Annual Meeting of Pharmaceutical Society of Japan, Tokyo, 1991

Special Symposium of Pharmaceutical Society of Japan, Tokyo, 1990

Annual Meeting of Chemical Society of Japan, Hiroshima, 1990

The Second International Symposium on the Chemical Synthesis of Antibiotics and Related Microbial Products, Oiso, Japan, 1990

Eighth International IUPAC Conference on Organic Synthesis, Helsinki, Finland, 1990

Third Belgian Organic Synthesis Symposium, Louvain-La-Neuve, Belgium, 1990

Midwestern Distinguished Lecturer, USA, 1990

The American Chemical Society, Aldrich Award Symposium, Boston, 1990

Fifth Japan-Korea Seminar on Organic Chemistry, Dae Jeon , Korea, 1990

PAC Meeting, Honolulu, 1989

Progress and Prospects in Organic Synthesis, Lausanne and Champery, Switzerland, 1989

11th International Symposium of Synthesis in Organic Chemistry, Oxford, UK, 1989

Visiting Professor of Universite Louis Pasteur, Strasbourg, 1989

Annual Meeting of Chemical Society of Japan, Kyoto, 1989

International Symposium of Acid-Base Catalysis, Sapporo, 1988

NATO Conference on Stereochemistry, Greece, 1988

IUPAC Conference on Natural Product, Kyoto, 1988

First Organic Reaction Lecturer, USA, 1988

Karl Pfizer Visiting Professor, MIT, 1988

Western Switzerland 3e Cycle Lecturer, 1987

Sheffield Stereochemistry Symposium, UK, 1987

Syntex Distinguished Lecturer, Colorado State University, 1987

Organic Synthesis Lecturer, University of California, Berkeley, 1987

IUPAC Conference on Organometallic Chemistry Directed Toward Organic Synthesis, Canada, 1987

Annual Meeting of Agricultural Society of Japan, Tokyo, 1987

Hoechst Conference on Stereochemistry, Germany, 1986

Gordon Conference on Stereochemistry, USA, 1986

Annual Meeting of Chemical Society of Korea, Seoul, 1986

Annual Meeting of Chemical Society of Japan, Tokyo, 1985

Euchem Stereochemistry Conference at Burgenstock, Switzerland, 1985

Annual Meeting of Pharmaceutical Society of Japan, Tokyo, 1984

IUPAC Conference on Organometallic Chemistry Directed Toward Organic Synthesis, France, 1983

IUPAC Conference on Organic Synthesis, Tokyo, 1982

PAC Meeting, Honolulu, USA, 1979

Pacific Coast Lecturer, USA, 1979

Awards

The Roger Adams Award, 2017

Fujiwara Prize, 2012

Noyori Prize, 2011

Member of American Academy of Arts and Sciences, 2011

Grand Prize of Synthetic Organic Chemistry of Japan, 2009

ACS Award for Creative Work in Synthetic Organic Chemistry, 2009

Honorary Member of the Chemical Society of Japan, 2008

The Japan Academy Award, 2007, Humboldt Research Award, 2007

The Karl-Ziegler Professorship, 2006

Tetrahedron Prize, 2006

Yamada Prize, 2004

Molecular Chirality Award, 2003, Fellow of American Association for the Advancement of Science, 2003

Tetrahedron Chair, 2002. Medal of Honor with Purple Ribbon (Japan), 2002

Max-Tishler Prize, 1998, Le Grand Prix de la Fondation Maison de la Chimie, 2002

The Chemical Society of Japan Award, 1995. Toray Science and Technology Award, 1997

Prelog Medal, 1993, Merck-Schuchardt Lectureship, 1994

IBM Science Award, 1988, Houkou Award, 1991, Chunichi Award, 1992

The Chemical Society of Japan Award for Young Chemist, 1977

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