CHUBU UNIVERSITY
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YAMAMOTO Yukiya

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Title Professor
Belong to Dept. of Biomedical Sciences
Center for Clinical Examination Practicum Support
Biomedical Sciences (graduate school)
Graduated Nagoya University Graduate School of Medicine
Degree Ph.D.
Qualification M.D., Fellow of the Japanese Society of Hematology, Fellow of the Japanese Society of Internal Medicine
Academic Institutional Membership European Hematology Association
American Society of Hematology
THE JAPANESE CANCER ASSOCIATION
THE JAPANESE SOCIETY OF HEMATOLOGY
THE JAPANESE SOCIETY OF INTERNAL MEDICINE
Field of Study Hematology and oncology
Research, Studies Mechanism of leukemogenesis, Developing novel therapies.

Academic Papers, Critique

Akinao Okamoto, Hidetsugu Fujigaki, Chisako Iriyama, Naoe Goto, Hideyuki Yamamoto, Keichiro Mihara, Yoko Inaguma, Yasuo Miura, Katsuya Furukawa, Yukiya Yamamoto, Yoshiki Akatsuka, Senji Kasahara, Kotaro Miyao, Masutaka Tokuda, Seiko Sato, Yuki Mizutani, Michiko Osawa, Keiko Hattori, Sachiko Iba, Ryoko Kajiya, Masataka Okamoto, Kuniaki Saito, Akihiro Tomita. CD19-positive lymphocyte count is critical for acquisition of anti-SARS-CoV-2 IgG after vaccination in B-cell lymphoma. Blood Adv bloodadvances. 2021006302.

Akihiro Abe, Yukiya Yamamoto, Akira Katsumi, Hideyuki Yamamoto, Akinao Okamoto, Yoko Inaguma, Chisako Iriyama, Masutaka Tokuda, Masataka Okamoto, Nobuhiko Emi, Akihiro Tomita. Truncated RUNX1 Generated by the Fusion of RUNX1 to Antisense GRIK2 via a Cryptic Chromosome Translocation Enhances Sensitivity to Granulocyte Colony-Stimulating Factor. Cytogenet Genome Res 160(5):255-263. 2020.

Abe A, Yamamoto Y, Katsumi A, Okamoto A, Tokuda M, Inaguma Y, Yamamoto K, Yanada M, Kanie T, Tomita A, Akatsuka Y, Okamoto M, Kameyama T, Mayeda A, Emi N: Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1-RUNX1T1 leukemia with t(8;12;21). International Journal of Hematology 108(2):208-212, 2018

Yanada M, Yamamoto Y (Co-first autoher), Iba S, Okamoto A, Inaguma Y, Tokuda M, Morishima S, Kanie T, Mizuta S, Akatsuka Y, Okamoto M, Emi N: TP53 mutations in older adults with acute myeloid leukemia. International Journal of Hematology 103(4):429-35, 2016

Abe A, Yamamoto Y, Iba S, Kanie T, Okamoto A, Tokuda M, Inaguma Y, Yanada M, Morishima S, Mizuta S, Akatsuka Y, Okamoto M, Kameyama T, Mayeda A, Emi N: ETV6-LPXN fusion transcript generated by t(11;12)(q12.1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9. Genes, Chromosomes and Cancer 55(3):242-50, 2016

Abe A, Yamamoto Y, Iba S, Okamoto A, Tokuda M, Inaguma Y, Yanada M, Morishima S, Kanie T, Tsuzuki M, Akatsuka Y, Mizuta S, Okamoto M, Kameyama T, Mayeda A, Emi N: NUP214-RAC1 and RAC1-COL12A1 Fusion in Complex Variant Translocations Involving Chromosomes 6, 7 and 9 in an Acute Myeloid Leukemia Case with DEK-NUP214. Cytogenetic and Genome Research 146(4):279-84, 2015

Yanada M, Okamoto A, Inaguma Y, Tokuda M, Morishima S, Kanie T, Yamamoto Y, Mizuta S, Akatsuka Y, Okamoto M, Emi N: The fate of patients with acute myeloid leukemia not undergoing induction chemotherapy. International Journal of Hematology 102(1):35-40, 2015

Yamamoto Y, Abe A, Emi N:Clarifying the impact of polycomb complex component disruption in human cancers. Molecular Cancer Research 12(4):479-84, 2014

Yamamoto Y, Tsuzuki S, Akahori Y, Ukai Y, Sumitomo M, Murayama Y, Yamamoto K, Inaguma Y, Tokuda M, Abe A, Akatsuka Y, Emi N, Kurosawa Y: Isolation of human mAbs that directly modulate FMS-related tyrosine kinase 3 signaling. Cancer Science 103(2):350-9, 2012

Yamamoto Y, Tsuzuki S, Tsuzuki M, Handa K, Inaguma Y, Emi N: BCOR as a novel fusion partner of retinoic acid receptor alpha in a t(X;17)(p11;q12) variant of acute promyelocytic leukemia. Blood 116(20): 4274-4283, 2010

Radomska HS, Basseres DS, Zheng R, Zhang P, Dayaram T, Yamamoto Y, Sternberg DW, Lokker N, Giese NA, Bohlander SK, Schnittger S, Delmotte MH, Davis RJ, Small D, Hiddemann W, Gilliland DG, Tenen DG: Block of C/EBPalpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations. Journal of Experimental Medicine 203(2):371-81, 2006

Minami Y, Kiyoi H, Yamamoto Y, Yamamoto K, Ueda R, Saito H, Naoe T: Selective apoptosis of tandemly duplicated FLT3-transformed leukemia cells by Hsp90 inhibitors. Leukemia 16(8):1535 -1340, 2002

Yamamoto Y, Kiyoi H, Nakano Y, Suzuki R, Kodera Y, Miyawaki S, Asou N, Kuriyama K, Yagasaki F, Shimazaki C, Akiyama H, Saito K,Nishimura M, Motoji T, Shinagawa K, Takeshita A, Saito H, Ueda R, Ohno R, Naoe T. Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies. Blood 97(8):2434-2439, 2001

Awards

Medical Research Fellowship of Takeda Science Foundation

KYO Award of Japanese Leukaemia Research Fund

Social Activities

Japanese Society of Hematology Councilor Medical advisor of MPN-JAPAN (Tokai region)

Perseus Proteomics Inc. Medical Expert

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