
IWAMOTO Takashi
Profile
Title | Professor |
---|---|
Belong to |
Dept. of Biomedical Sciences Center for Education in Laboratory Animal Research Center for Clinical Examination Practicum Support Biomedical Sciences (graduate school) |
Graduated | Nagoya University, Graduate School of Medicine |
Degree | Dr. of Medicine, Nagoya University |
Academic Institutional Membership | The Molecular Biology Society of Japan Japanese Cancer Association Society for Neuroscience Japanese Association for Laboratory Animal Science |
Field of Study | Molecular Biology |
Research, Studies | Analysis of miRNAs on cardiomyopathy, cognitive neuroscience and cancer |
Curriculum Specialized | Laboratory Animal Research, Oncology, Genetic Engineering |
Academic Papers, Critique
Forced expression of miR-143 and -145 in cardiomyocytes induces cardiomyopathy with a reductive redox shift. Cell Mol Biol Lett, 25:40, 2020
Simple and large-scale chromosomal engineering of mouse zygotes via in vitro and in vivo electroporation. Scientific Reports, 914713, 2019
Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension. Clin Exp Hypertens. Jun 14:1-5, 2018
The normality of sperm in an infertile man with ring chromosome 15: a case report.J Assist Reprod Genet. 35: 251-256, 2018
Testis-Specific Histone Variant H3t Gene is Essential for Entry into Spermatogenesis. Cell Reports 18:593-600, 2016
Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents. Mol Cell Biochem. 403(1-2):231-41, 2015
Emerging evidence of insulin-like growth factor 2 as a memory enhancer: a unique animal model of cognitive dysfunction with impaired adult neurogenesis. Rev Neurosci. 25(4) 559-574, 2014
The Heterochronic Genes lin-28a and lin-28b play an Essential and Evolutionarily Conserved Role in Early Zebrafish development. PLoS One. 9(2):e88086, 2014
G protein-coupled receptor 43 moderates gut inflammation through cytokine regulation from mononuclear cells. Inflamm Bowel Dis. 19:2848-2856, 2013
Deficits in microRNA-mediated Cxcr4/Cxcl12 signaling in neurodevelopmental deficits in a 22q11 deletion syndrome mouse model. Proc Natl Acad Sci U S A. 110:17552-17557, 2013
Reduced adult hippocampal neurogenesis and working memory deficits in the Dgcr8-deficient mouse model of 22q11.2 deletion-associated schizophrenia can be rescued by IGF2. J Neurosci. 33:9408-9419, 2013
Forced Expression of miR-143 Represses ERK5/c-Myc and p68/p72 Signaling in Concert with miR-145 in Gut Tumors of ApcMin Mice. PLoS ONE 7(8):e42137, 2012
A novel hairless mouse model for malignant melanoma. J Dermatol Sci. 65:207-212, 2012
Mimosine-Induced Apoptosis in C6 Glioma Cells Requires the Release of Mitochondria-Derived Reactive Oxygen Species and p38, JNK Activation. Neurochem Res. 37:417-427, 2011
β-Catenin signaling regulates the timing of cell differentiation in mouse retinalprogenitor cells. Mol Cell Neurosci. 46(4):770-780, 2011
Modulation of microRNA processing by p53. Nature 460:529-533, 2009
A role for AP-1 in matrix metalloproteinase production and invadopodia formation of v-Crk-transformed cells. Exp Cell Res. 315:1384-1392, 2009
Establishment of cells to monitor Microprocessor through fusion genes of microRNA and GFP. Biochem Biophys Res Commun. 372:856-861, 2008
Functional analysis of the effect of forced activation of STAT3 on M1 mouse leukemia cells. Int. J Mol. Med. 15:269-75, 2005
Stat3-dependent induction of interleukin-3 receptor expression in leukemia inhibitory factor-stimulated M1 mouse leukemia cells. Cytokine, 25:136-139, 2004
LSSIG is a novel murine leukocyte-specific GPCR that is induced by the activation of STAT3. Blood, 101:1185-1187, 2003
Stat3-dependent induction of BATF in M1 mouse myeloid leukemia cells. Oncogene, 21: 8186-8191, 2002
JAK/Stat3 dependent activation of RalGDS/Ral pathway in M1 mouse myeloid leukemia cells. J. Biol. Chem., 276: 32678-32681, 2001
The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation. Oncogene, 19: 4795-4801, 2000
Transgenic mouse model for skin malignant melanoma. Oncogene. 17: 1885-8. 1998
cDNA cloning of mouse ret proto-oncogene and its sequence similarity to the cadherin superfamily. Oncogene. 8: 1087-91. 1993
Accelerated proliferation and interleukin-2 production of thymocytes by stimulation of soluble anti-CD3 monoclonal antibody in transgenic mice carrying a rabbit protein kinase C. J. Biol. Chem. 267: 18644-18648, 1992
Aberrant melanogenesis and melanocytic tumor development in transgenic mice that carry metallothionein/ret fusion gene. EMBO J. 10: 3167-3175, 1991