上村　和秀　UEMURA Kazuhide

プロフィール

職名	准教授
所属	生命健康科学部 理学療法学科 生命健康科学部 生命医科学科 理学療法実習センター 大学院 生命健康科学研究科 生命医科学専攻
最終学歴	京都大学大学院薬学研究科博士後期課程修了
学位	博士（薬学）
資格	薬剤師
所属学会・役職	日本薬学会 日本糖質学会
専門分野	薬理学、病態生化学
研究テーマ	炎症性疾患における動物レクチンの役割
授業科目	薬理学、生化学
共同研究キーワード	糖鎖、レクチン、腎臓病、炎症、抗酸化物質

学術論文、評論

“Antioxidant Effects Of The Hydroxyl Groups In The Simple Phenolic Carbazoles.” Hieda Y, Hatae N, Anraku M, Matsuura N, Uemura K, Hibino S, Choshi T, Tomida H, Hori O, and Fujioka H. Heterocycles, 92(1), 120-132 (2016)

“Sairei-to Ameliorates Rat Peritoneal Fibrosis Partly through Suppression of Oxidative Stress.” Kitamoto M, Kato K, Sugimoto A, Kitamura H, Uemura K, Takeda T, Wu C, Nogaki F, Morimoto T, Ono T. Nephron Experimental Nephrology 117: e71-e81. (2011)

“Lipopolysaccharide-triggered acute aggravation of mesangioproliferative glomerulonephritis through activation of coagulation in a high IgA strain of ddY mice.” Shimosawa M, Sakamoto K, Tomari Y, Kamikado K, Otsuka H, Liu N, Kitamura H, Uemura K, Nogaki F, Mori N, Muso E, Yoshida H, Ono T. Nephron Experimental Nephrology 112: e81-e91. (2009)

“Tissue factor and factor V involvement in rat peritoneal fibrosis.” Saito H, Kitamoto M, Kato K, Liu N, Kitamura H, Uemura K, Nogaki F, Takeda T, Mori N, Ono T. Peritoneal Dialysis International 29: 340-351. (2009)

“Serofendic acid protects from iodinated contrast medium and high glucose probably against superoxide production in LLC-PK1 cells.” Kitamura O, Uemura K, Kitamura H, Sugimoto H, Akaike A, Ono T. Clinical and Experimental Nephrology 13: 15-24. (2009)

“Roles of Pofut1 and O-fucose in mammalian Notch signaling.” Uemura K, Stahl M, Ge C, Shi S, Tashima Y, Stanley P. The Journal of Biological Chemistry 283: 13638-13651. (2008)

“Soluble fibrin formation in the mesangial area of IgA nephropathy.” Liu N, Mori N, Iehara N, Uemura K, Fukastu A, Kita T, Matsuda M, Ono T. Clinical and Experimental Nephrology 11, 71-76. (2007)

“The Na+-excreting efficacy of indapamide in combination with furosemide in massive edema.” Tanaka M, Oida E, Nomura K, Nogaki F, Fukatsu A, Uemura K, Yashiro M, Kimura T, Muso E, Ono T. Clinical and Experimental Nephrology 9, 122-126. (2005)

“Superoxide production from human polymorphonuclear leukocytes by human mannan-binding protein (MBP).” Uemura K, Yamamoto H, Nakagawa T, Nakamura K, Kawasaki N, Oka S, Ma BY, Kawasaki T. Glycoconjugate Journal 21, 79-84. (2004)

“Antitumor activity of mannan-binding protein.” Nakagawa T, Kawasaki N, Ma BY, Uemura K, Kawasaki T. Methods in Enzymology 363, 26-33. (2003)

“Preparation of recombinant mannan-binding protein with a native oligomeric structure.” Uemura K, Ma BY, Nakagawa T, Kawasaki N, Kawasaki T. Methods in Enzymology 363, 16-26. (2003)

“Role of mannan-binding protein, MBP, in innate immunity.” Nakagawa T, Ma BY, Uemura K, Oka S, Kawasaki N, Kawasaki T. Anticancer Research 23, 4467-4471. (2003)

“High mannose glycans and sialic acid on gp120 regulate binding of mannose-binding lectin (MBL) to HIV type 1.” Hart ML, Saifuddin M, Uemura K, Bremer EG, Hooker B, Kawasaki T, Spear GT. AIDS Research and Human Retroviruses 18, 1311-1317. (2002)

“L-MBP is expressed in epithelial cells of mouse small intestine.” Uemura K, Saka M, Nakagawa T, Kawasaki N, Thiel S, Jensenius JC, Kawasaki T.

The Journal of Immunology 169, 6945-6950. (2002)

“Tail-vein injection of mannan-binding lectin DNA leads to high expression levels of multimeric protein in liver.” Vorup-Jensen T, Jensen UB, Liu H, Kawasaki T, Uemura K, Thiel S, Dagnaes-Hansen F, Jensen TG. Molecular Therapy 3, 867-874. (2001)

“Recombinant expression of human mannan-binding lectin.” Vorup-Jensen T, Sorensen ES, Jensen UB, Schwaeble W, Kawasaki T, Ma Y, Uemura K, Wakamiya N, Suzuki Y, Jensen TG, Takahashi K, Ezekowitz RA, Thiel S, Jensenius JC.

International Immunopharmacology 1, 677-687. (2001)

“Antitumor activity of mannan-binding protein in vivo as revealed by a virus expression system: mannan-binding proteindependent cell-mediated cytotoxicity.” Ma Y, Uemura K, Oka S, Kozutsumi Y, Kawasaki N, Kawasaki T. Proceedings of the National Academy of Sciences of the United States of America 96, 371-375. (1999)

“Characterization of human serum mannan-binding protein promoter.” Naito H, Ikeda A, Hasegawa K, Oka S, Uemura K, Kawasaki N, Kawasaki T. The Journal of Biochemistry 126, 1004-1012. (1999)

“Metabolic properties of normal and mutant mannan-binding proteins in mouse plasma.” Naito H, Ma Y, Uemura K, Arano Y, Kawasaki T. Biochemical and Biophysical Research Communications 256, 231-234. (1999)

“A unique CD45 glycoform recognized by the serum mannan-binding protein in immature thymocytes.” Uemura K, Yokota Y, Kozutsumi Y, Kawasaki T. The Journal of Biological Chemistry 271, 4581-4584. (1996)